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Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25461354

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

About this item

Full title

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (10), p.3992-3997

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Vertebrates express at least 15 different synaptotagmins with the same domain structure but diverse localizations and tissue distributions. Synaptotagmin-1,-2, and -9 act as calcium sensors for the fast phrase of neurotransmitter release, and synaptotagmin-12 acts as a calcium-independent modulator of release. The exact functions of the remaining 1...

Alternative Titles

Full title

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_25461354

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25461354

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0711700105

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