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Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25593136

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

About this item

Full title

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (45), p.19023-19028

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Muscular dystrophy is a general term encompassing muscle disorders that cause weakness and wasting, typically leading to premature death. Membrane instability, as a result of a genetic disruption within the dystrophin-glycoprotein complex (DGC), is thought to induce myofiber degeneration, although the downstream mechanism whereby membrane fragility...

Alternative Titles

Full title

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_25593136

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25593136

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0906591106

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