Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism
Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Muscular dystrophy is a general term encompassing muscle disorders that cause weakness and wasting, typically leading to premature death. Membrane instability, as a result of a genetic disruption within the dystrophin-glycoprotein complex (DGC), is thought to induce myofiber degeneration, although the downstream mechanism whereby membrane fragility...
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Full title
Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism
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TN_cdi_jstor_primary_25593136
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25593136
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0906591106