IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting...
IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells
About this item
Full title
Author / Creator
Guenova, Emmanuella , Skabytska, Yuliya , Hoetzenecker, Wolfram , Weindl, Günther , Sauer, Karin , Tham, Manuela , Kim, Kyu-Won , Park, Ji-Hyeon , Seo, Ji Hae , Ignatova, Desislava , Cozzio, Antonio , Levesque, Mitchell P. , Volz, Thomas , Köberle, Martin , Kaesler, Susanne , Thomas, Peter , Mailhammer, Reinhard , Ghoreschi, Kamran , Schäkel, Knut , Amarov, Boyko , Eichner, Martin , Schaller, Martin , Clark, Rachael A. , Röcken, Martin and Biedermann, Tilo
Publisher
National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Interleukin 4 (IL-4) can suppress delayed-type hypersensitivity reactions (DTHRs), including organ-specific autoimmune diseases in mice and humans. Despite the broadly documented antiinflammatory effect of IL-4, the underlying mode of action remains incompletely understood, as IL-4 also promotes IL-12 production by dendritic cells (DCs) and IFN-γ–p...
Alternative Titles
Full title
IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells
Authors, Artists and Contributors
Author / Creator
Skabytska, Yuliya
Hoetzenecker, Wolfram
Weindl, Günther
Sauer, Karin
Tham, Manuela
Kim, Kyu-Won
Park, Ji-Hyeon
Seo, Ji Hae
Ignatova, Desislava
Cozzio, Antonio
Levesque, Mitchell P.
Volz, Thomas
Köberle, Martin
Kaesler, Susanne
Thomas, Peter
Mailhammer, Reinhard
Ghoreschi, Kamran
Schäkel, Knut
Amarov, Boyko
Eichner, Martin
Schaller, Martin
Clark, Rachael A.
Röcken, Martin
Biedermann, Tilo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_26461605
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26461605
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1416922112
