SPARC triggers a cell-autonomous program of synapse elimination
SPARC triggers a cell-autonomous program of synapse elimination
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Elimination of the excess synaptic contacts established in the early stages of neuronal development is required to refine the function of neuronal circuits. Here we investigate whether secreted protein acidic and rich in cysteine (SPARC), a molecule produced by glial cells, is involved in synapse removal. SPARC production peaks when innervation of...
Alternative Titles
Full title
SPARC triggers a cell-autonomous program of synapse elimination
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_jstor_primary_26465781
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26465781
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1512202112
