MicroRNA-3151 inactivates TP53 inBRAF-mutated human malignancies
MicroRNA-3151 inactivates TP53 inBRAF-mutated human malignancies
About this item
Full title
MicroRNA-3151 inactivates TP53 inBRAF-mutated human malignancies
Author / Creator
Publisher
National Academy of Sciences
Journal title
Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (49), p.E6744-E6751
Language
English
Formats
Publication information
Publisher
National Academy of Sciences
More information
Scope and Contents
Contents
TheB-Raf proto-oncogene serine/threonine kinase(BRAF) gene is the most frequently mutated gene in malignant melanoma (MM) and papillary thyroid cancer (PTC) and is causally involved in malignant cell transformation. Mutated BRAF is associated with an aggressive disease phenotype, thus making it a top candidate for targeted treatment strategies in M...
Alternative Titles
Full title
MicroRNA-3151 inactivates TP53 inBRAF-mutated human malignancies
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_26466564
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26466564
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
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