Distinct recognition of complement iC3b by integrins αXβ₂ and αMβ
Distinct recognition of complement iC3b by integrins αXβ₂ and αMβ
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Publisher
National Academy of Sciences
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Language
English
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Publisher
National Academy of Sciences
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Contents
Recognition by the leukocyte integrins αXβ₂ and αMβ₂ of complement iC3b-opsonized targets is essential for effector functions including phagocytosis. The integrin-binding sites on iC3b remain incompletely characterized. Here, we describe negative-stain electron microscopy and biochemical studies of αXβ₂ and αMβ₂ in complex with iC3b. Despite high h...
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Full title
Distinct recognition of complement iC3b by integrins αXβ₂ and αMβ
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TN_cdi_jstor_primary_26480337
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26480337
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ISSN
0027-8424
E-ISSN
1091-6490