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Structure-based approach to rationally design a chimeric protein for an effective vaccine against Gr...

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Gr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_27978597

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

About this item

Full title

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (25), p.10278-10283

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Structural vaccinology is an emerging strategy for the rational design of vaccine candidates. We successfully applied structural vaccinology to design a fully synthetic protein with multivalent protection activity. In Group B Streptococcus, cell-surface pili have aroused great interest because of their direct roles in virulence and importance as pr...

Alternative Titles

Full title

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_27978597

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_27978597

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1106590108

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