Leukocyte Adhesion during Hypoxia Is Mediated by HIF-1-Dependent Induction of β2Integrin Gene Expres...
Leukocyte Adhesion during Hypoxia Is Mediated by HIF-1-Dependent Induction of β2Integrin Gene Expression
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Publisher
National Academy of Sciences
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Language
English
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Publisher
National Academy of Sciences
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Contents
Inflammatory responses are associated with significant changes in tissue metabolism. In particular, metabolic shifts during inflammation can result in significant tissue hypoxia, with resultant induction of hypoxia-responsive genes. Given this association, we hypothesized that leukocyte functional responses are influenced by hypoxia. Initial experi...
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Full title
Leukocyte Adhesion during Hypoxia Is Mediated by HIF-1-Dependent Induction of β2Integrin Gene Expression
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TN_cdi_jstor_primary_3372910
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_3372910
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0401339101
