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The Beginnings of Mucin Biosynthesis: The Crystal Structure of UDP-GalNAc:Polypeptide α-N-Acetylgala...

The Beginnings of Mucin Biosynthesis: The Crystal Structure of UDP-GalNAc:Polypeptide α-N-Acetylgala...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_3373516

The Beginnings of Mucin Biosynthesis: The Crystal Structure of UDP-GalNAc:Polypeptide α-N-Acetylgalactosaminyltransferase-T1

About this item

Full title

The Beginnings of Mucin Biosynthesis: The Crystal Structure of UDP-GalNAc:Polypeptide α-N-Acetylgalactosaminyltransferase-T1

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2004-10, Vol.101 (43), p.15307-15312

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferases (pp-GaNTases) initiate the formation of mucin-type, O-linked glycans by catalyzing the transfer of α-N-acetylgalactosamine from UDP-GalNAc to Ser or Thr residues of core proteins to form the Tn antigen (GalNAc-α-1-O-Ser/Thr). ppGaNTases are unique among glycosyltransferases in containing a...

Alternative Titles

Full title

The Beginnings of Mucin Biosynthesis: The Crystal Structure of UDP-GalNAc:Polypeptide α-N-Acetylgalactosaminyltransferase-T1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_3373516

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_3373516

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0405657101

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