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Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway

Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_42590532

Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway

About this item

Full title

Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (17), p.6877-6882

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Increasing evidence points to a role for the protein quality control in the endoplasmic reticulum (ER) in maintaining intestinal homeostasis. However, the specific role for general ER chaperones in this process remains unknown. Herein, we report that a major ER heat shock protein grp94 interacts with MesD, a critical chaperone for the Wnt corecepto...

Alternative Titles

Full title

Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_42590532

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_42590532

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1302933110

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