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Protein kinase Cβ as a therapeutic target stabilizing blood–brain barrier disruption in experimental...

Protein kinase Cβ as a therapeutic target stabilizing blood–brain barrier disruption in experimental...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_42713183

Protein kinase Cβ as a therapeutic target stabilizing blood–brain barrier disruption in experimental autoimmune encephalomyelitis

About this item

Full title

Protein kinase Cβ as a therapeutic target stabilizing blood–brain barrier disruption in experimental autoimmune encephalomyelitis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (36), p.14735-14740

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Disruption of the blood–brain barrier (BBB) is a hallmark of acute inflammatory lesions in multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis. This disruption may precede and facilitate the infiltration of encephalitogenic T cells. The signaling events that lead to this BBB disruption are incompletely understood...

Alternative Titles

Full title

Protein kinase Cβ as a therapeutic target stabilizing blood–brain barrier disruption in experimental autoimmune encephalomyelitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_42713183

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_42713183

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1302569110

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