Curcumin Derivatives Inhibit or Modulate Beta-Amyloid Precursor Protein Metabolism
Curcumin Derivatives Inhibit or Modulate Beta-Amyloid Precursor Protein Metabolism
Curcumin Derivatives Inhibit or Modulate Beta-Amyloid Precursor Protein Metabolism
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Publisher
Basel, Switzerland: S. Karger AG
Journal title
Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Scope and Contents
Contents
Curcumin-derived oxazoles and pyrazoles were synthesized in order to minimize the metal chelation properties of curcumin. The reduced rotational freedom and the absence of stereoisomers was anticipated to enhance the inhibition of γ-secretase. Accordingly, the replacement of the 1,3-dicarbonyl moiety by isosteric heterocycles turned curcumin analog...
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Full title
Curcumin Derivatives Inhibit or Modulate Beta-Amyloid Precursor Protein Metabolism
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Author / Creator
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Record Identifier
TN_cdi_karger_primary_101832
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_101832
Other Identifiers
ISBN
3805583397,9783805583398
ISSN
1660-2854
E-ISSN
1660-2862
DOI
10.1159/000101832
