Sclerostin and Bone Aging: A Mini-Review
Sclerostin and Bone Aging: A Mini-Review
About this item
Full title
Author / Creator
Publisher
Basel, Switzerland: S. Karger AG
Journal title
Language
English
Formats
Publication information
Publisher
Basel, Switzerland: S. Karger AG
Subjects
More information
Scope and Contents
Contents
Sclerostin, mainly produced by osteocytes, is now considered a major regulator of bone formation. Identified from patients with a low bone mass, sclerostin inhibits the Wnt pathway by binding to LRP5/6 and subsequently increases bone formation. Sclerostin may also play a role in the mediation of systemic and local factors such as calcitriol, PTH, g...
Alternative Titles
Full title
Sclerostin and Bone Aging: A Mini-Review
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_karger_primary_446278
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_446278
Other Identifiers
ISSN
0304-324X
E-ISSN
1423-0003
DOI
10.1159/000446278
