Rapid Screen of IL-5/IL-5Rα Blocking Antibodies in the HEK293-IL-5Rα-CSF2RB Transfected Cell Line
Rapid Screen of IL-5/IL-5Rα Blocking Antibodies in the HEK293-IL-5Rα-CSF2RB Transfected Cell Line
About this item
Full title
Author / Creator
Li, Shijie , Han, Fei , Liu, Chang , Dai, Weiyan , Ke, Wenfeng , Chen, Yongqi , Fordjour, Eric , Yang, Yankun and Bai, Zhonghu
Publisher
Seoul: The Korean Society for Biotechnology and Bioengineering
Journal title
Language
English
Formats
Publication information
Publisher
Seoul: The Korean Society for Biotechnology and Bioengineering
Subjects
More information
Scope and Contents
Contents
Interleukin-5 (IL-5) binding to interleukin-5 receptor subunit alpha (IL-5Rα) increases the number of eosinophils and enhances eosinophil activity. This leads to eosinophil tissue infiltration and damage to the lungs, ultimately resulting in exacerbation of asthma. Antibodies that block IL-5 binding to IL-5Rα are thought to play an important role i...
Alternative Titles
Full title
Rapid Screen of IL-5/IL-5Rα Blocking Antibodies in the HEK293-IL-5Rα-CSF2RB Transfected Cell Line
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10321453
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10321453
Other Identifiers
ISSN
1226-8372
E-ISSN
1976-3816
DOI
10.1007/s12257-022-0315-2
