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FGFR3 drives Aβ-induced tau uptake

FGFR3 drives Aβ-induced tau uptake

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10585215

FGFR3 drives Aβ-induced tau uptake

About this item

Full title

FGFR3 drives Aβ-induced tau uptake

Publisher

London: Nature Publishing Group UK

Journal title

Experimental and Molecular Medicine, 2024, 56(0), , pp.1631-1642

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The amyloid cascade hypothesis suggests that amyloid beta (Aβ) contributes to initiating subsequent tau pathology in Alzheimer’s disease (AD). However, the underlying mechanisms through which Aβ contributes to tau uptake and propagation remain poorly understood. Here, we show that preexisting amyloid pathology accelerates the uptake of extracellula...

Alternative Titles

Full title

FGFR3 drives Aβ-induced tau uptake

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10585215

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10585215

Other Identifiers

ISSN

2092-6413,1226-3613

E-ISSN

2092-6413

DOI

10.1038/s12276-024-01274-3

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