TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury...
TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD
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Author / Creator
Publisher
Korea (South): Korean Association for the Study of the Liver
Journal title
Language
English
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Publication information
Publisher
Korea (South): Korean Association for the Study of the Liver
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Scope and Contents
Contents
Backgrounds/Aims: Transmembrane 6 superfamily member 2 (TM6SF2) E167K variant is closely associated with the occurrence and development of metabolic dysfunction-associated steatotic liver disease (MASLD). However, the role and mechanism of TM6SF2 E167K variant during MASLD progression are not yet fully understood.Methods: The Tm6sf2167K knock-in (K...
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Full title
TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD
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Record Identifier
TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10637181
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10637181
Other Identifiers
ISSN
2287-2728,2287-285X
E-ISSN
2287-285X
DOI
10.3350/cmh.2024.0268