SUMOylation of TP53INP1 is involved in miR-30a-5p-regulated heart senescence
SUMOylation of TP53INP1 is involved in miR-30a-5p-regulated heart senescence
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Author / Creator
Hong, Yi-Xiang , Wu, Chan , Li, Jing-Zhou , Song, Fei , Hu, Yu , Han, Yue , Mao, Yi-Jie , Wu, Wei-Yin , Wang, Yan and Li, Gang
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Heart senescence is critical for cardiac function. This study aimed to characterize the role and mechanism of action of miR-30a-5p in cardiac senescence. miR-30a-5p was downregulated in aged mouse hearts and neonatal rat cardiomyocytes (NRCMs). In vivo, using a combination of echocardiography and different molecular biological approaches, we invest...
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Full title
SUMOylation of TP53INP1 is involved in miR-30a-5p-regulated heart senescence
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TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10650549
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10650549
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ISSN
2092-6413,1226-3613
E-ISSN
2092-6413
DOI
10.1038/s12276-024-01347-3