Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate
Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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The crystal structure of human stearoyl-CoA desaturase-1 in complex with its natural substrate provides a close-up view of a key enzymatic step in the synthesis of unsaturated fatty acids.
Stearoyl–coenzyme A desaturase-1 (SCD1) has an important role in lipid metabolism, and SCD1 inhibitors are potential therapeutic agents for the treatment of m...
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Full title
Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate
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TN_cdi_osti_scitechconnect_1213738
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_1213738
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.3049
