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Structure and dynamics of a constitutively active neurotensin receptor

Structure and dynamics of a constitutively active neurotensin receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_1346248

Structure and dynamics of a constitutively active neurotensin receptor

About this item

Full title

Structure and dynamics of a constitutively active neurotensin receptor

Publisher

United States: Nature Publishing Group

Journal title

Scientific reports, 2016-12, Vol.6 (12, 2016)

Language

English

Formats

Publication information

Publisher

United States: Nature Publishing Group

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Many G protein-coupled receptors show constitutive activity, resulting in the production of a second messenger in the absence of an agonist; and naturally occurring constitutively active mutations in receptors have been implicated in diseases. To gain insight into mechanistic aspects of constitutive activity, we report here the 3.3 Å crystal struct...

Alternative Titles

Full title

Structure and dynamics of a constitutively active neurotensin receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_osti_scitechconnect_1346248

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_1346248

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

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