Structural insights into the activation of metabotropic glutamate receptors
Structural insights into the activation of metabotropic glutamate receptors
About this item
Full title
Author / Creator
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS) , Koehl, Antoine , Hu, Hongli , Feng, Dan , Sun, Bingfa , Zhang, Yan , Robertson, Michael J. , Chu, Matthew , Kobilka, Tong Sun , Laeremans, Toon , Steyaert, Jan , Tarrasch, Jeffrey , Dutta, Somnath , Fonseca, Rasmus , Weis, William I. , Mathiesen, Jesper M. , Skiniotis, Georgios and Kobilka, Brian K.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Metabotropic glutamate receptors are family C G-protein-coupled receptors. They form obligate dimers and possess extracellular ligand-binding Venus flytrap domains, which are linked by cysteine-rich domains to their 7-transmembrane domains. Spectroscopic studies show that signalling is a dynamic process, in which large-scale conformational changes...
Alternative Titles
Full title
Structural insights into the activation of metabotropic glutamate receptors
Authors, Artists and Contributors
Author / Creator
Koehl, Antoine
Hu, Hongli
Feng, Dan
Sun, Bingfa
Zhang, Yan
Robertson, Michael J.
Chu, Matthew
Kobilka, Tong Sun
Laeremans, Toon
Steyaert, Jan
Tarrasch, Jeffrey
Dutta, Somnath
Fonseca, Rasmus
Weis, William I.
Mathiesen, Jesper M.
Skiniotis, Georgios
Kobilka, Brian K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_osti_scitechconnect_1497167
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_1497167
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-0881-4
