A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma
A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma
About this item
Full title
Author / Creator
Kakiuchi-Kiyota, Satoko , Ross, Thorsten , Wallweber, Heidi Ackerly , Kiefer, James R. , Schutten, Melissa M. , Adedeji, Adeyemi O. , Cai, Hao , Hendricks, Robert , Cohen, Sivan , Myneni, Srividya , Liu, Luna , Fullerton, Aaron , Corr, Nicholas , Yu, Lanlan , de Almeida Nagata, Denise , Zhong, Shelly , Leong, Steven R. , Li, Ji , Nakamura, Rin , Sumiyoshi, Teiko , Li, Jinze , Ovacik, Ayse Meric , Zheng, Bing , Dillon, Mike , Spiess, Christoph , Wingert, Susanne , Rajkovic, Erich , Ellwanger, Kristina , Reusch, Uwe , Polson, Andrew G. and SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States). Stanford Synchrotron Radiation Lightsource (SSRL)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Despite the recent progress, multiple myeloma (MM) is still essentially incurable and there is a need for additional effective treatments with good tolerability. RO7297089 is a novel bispecific BCMA/CD16A-directed innate cell engager (ICE
®
) designed to induce BCMA+ MM cell lysis through high affinity binding of CD16A and retargeting of NK c...
Alternative Titles
Full title
A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma
Authors, Artists and Contributors
Author / Creator
Ross, Thorsten
Wallweber, Heidi Ackerly
Kiefer, James R.
Schutten, Melissa M.
Adedeji, Adeyemi O.
Cai, Hao
Hendricks, Robert
Cohen, Sivan
Myneni, Srividya
Liu, Luna
Fullerton, Aaron
Corr, Nicholas
Yu, Lanlan
de Almeida Nagata, Denise
Zhong, Shelly
Leong, Steven R.
Li, Ji
Nakamura, Rin
Sumiyoshi, Teiko
Li, Jinze
Ovacik, Ayse Meric
Zheng, Bing
Dillon, Mike
Spiess, Christoph
Wingert, Susanne
Rajkovic, Erich
Ellwanger, Kristina
Reusch, Uwe
Polson, Andrew G.
SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States). Stanford Synchrotron Radiation Lightsource (SSRL)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_osti_scitechconnect_1982096
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_1982096
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-021-01478-w
