A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonucle...
A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1
About this item
Full title
Author / Creator
Das, Debanu , Duncton, Matthew A. J. , Georgiadis, Taxiarchis M. , Pellicena, Patricia , Clark, Jennifer , Sobol, Robert W. , Georgiadis, Millie M. , King-Underwood, John , Jobes, David V. , Chang, Caleb , Gao, Yang , Deacon, Ashley M. , Wilson, David M. and SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States). Stanford Synchrotron Radiation Lightsource (SSRL)
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
The ability to quickly discover reliable hits from screening and rapidly convert them into lead compounds, which can be verified in functional assays, is central to drug discovery. The expedited validation of novel targets and the identification of modulators to advance to preclinical studies can significantly increase drug development success. Our...
Alternative Titles
Full title
A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1
Authors, Artists and Contributors
Author / Creator
Duncton, Matthew A. J.
Georgiadis, Taxiarchis M.
Pellicena, Patricia
Clark, Jennifer
Sobol, Robert W.
Georgiadis, Millie M.
King-Underwood, John
Jobes, David V.
Chang, Caleb
Gao, Yang
Deacon, Ashley M.
Wilson, David M.
SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States). Stanford Synchrotron Radiation Lightsource (SSRL)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_osti_scitechconnect_2471709
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_2471709
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms242316637
