Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease
Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Prion diseases are a group of invariably fatal neurodegenerative disorders affecting humans and a wide range of mammals. An essential part of the infectious agent, termed the prion, is composed of an abnormal isoform (PrPSc) of a host-encoded normal cellular protein (PrPC). The conversion of PrPC to PrPSc is thought to play a crucial role in the de...
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Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease
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TN_cdi_plos_journals_1288079642
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1288079642
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ISSN
1549-1676,1549-1277
E-ISSN
1549-1676
DOI
10.1371/journal.pmed.0030014
