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Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second st...

Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second st...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1288106708

Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis

About this item

Full title

Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2012-07, Vol.6 (7), p.e1734

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Medicines against second stage HAT, where parasites have invaded the central nervous system (CNS). The pharmacology of a potential orally available lead...

Alternative Titles

Full title

Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1288106708

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1288106708

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0001734

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