A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factor...
A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease
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Author / Creator
Couderc, Thérèse , Chrétien, Fabrice , Schilte, Clémentine , Disson, Olivier , Brigitte, Madly , Guivel-Benhassine, Florence , Touret, Yasmina , Barau, Georges , Cayet, Nadège , Schuffenecker, Isabelle , Desprès, Philippe , Arenzana-Seisdedos, Fernando , Michault, Alain , Albert, Matthew L and Lecuit, Marc
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Chikungunya virus (CHIKV) is a re-emerging arbovirus responsible for a massive outbreak currently afflicting the Indian Ocean region and India. Infection from CHIKV typically induces a mild disease in humans, characterized by fever, myalgia, arthralgia, and rash. Cases of severe CHIKV infection involving the central nervous system (CNS) have recent...
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Full title
A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease
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TN_cdi_plos_journals_1289042433
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289042433
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.0040029
