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Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on...

Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289061633

Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway

About this item

Full title

Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2009-10, Vol.5 (10), p.e1000618-e1000618

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Many viruses encode proteins whose major function is to evade or disable the host T cell response. Nevertheless, most viruses are readily detected by host T cells, and induce relatively strong T cell responses. Herein, we employ transgenic CD4(+) and CD8(+) T cells as sensors to evaluate in vitro and in vivo antigen presentation by coxsackievirus B...

Alternative Titles

Full title

Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289061633

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289061633

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1000618

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