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Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ

Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289064837

Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ

About this item

Full title

Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-01, Vol.8 (1), p.e53243-e53243

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A definitive consequence of the aging process is the progressive deterioration of higher cognitive functions. Defects in DNA repair mechanisms mostly result in accelerated aging and reduced brain function. DNA polymerase µ is a novel accessory partner for the non-homologous end-joining DNA repair pathway for double-strand breaks, and its deficiency...

Alternative Titles

Full title

Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289064837

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289064837

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0053243

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