Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ
Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
A definitive consequence of the aging process is the progressive deterioration of higher cognitive functions. Defects in DNA repair mechanisms mostly result in accelerated aging and reduced brain function. DNA polymerase µ is a novel accessory partner for the non-homologous end-joining DNA repair pathway for double-strand breaks, and its deficiency...
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Full title
Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ
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TN_cdi_plos_journals_1289064837
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289064837
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0053243