Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response
Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
In this communication, we demonstrate that galectin (Gal)-9 acts to constrain CD8(+) T cell immunity to Herpes Simplex Virus (HSV) infection. In support of this, we show that animals unable to produce Gal-9, because of gene knockout, develop acute and memory responses to HSV that are of greater magnitude and better quality than those that occur in...
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Full title
Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response
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TN_cdi_plos_journals_1289068776
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289068776
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1000882
