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Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial transloca...

Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial transloca...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289070247

Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation

About this item

Full title

Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2010-04, Vol.6 (4), p.e1000852

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

While several clinical studies have shown that HIV-1 infection is associated with increased permeability of the intestinal tract, there is very little understanding of the mechanisms underlying HIV-induced impairment of mucosal barriers. Here we demonstrate that exposure to HIV-1 can directly breach the integrity of mucosal epithelial barrier, allo...

Alternative Titles

Full title

Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289070247

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289070247

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1000852

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