Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with r...
Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Radiation-attenuated Plasmodium sporozoites (RAS) are the only vaccine shown to induce sterilizing protection against malaria in both humans and rodents. Importantly, these "whole-parasite" vaccines are currently under evaluation in human clinical trials. Studies with inbred mice reveal that RAS-induced CD8 T cells targeting liver-stage parasites a...
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Full title
Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites
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TN_cdi_plos_journals_1289076425
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289076425
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1000998
