CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope
CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope
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Author / Creator
Cardinaud, Sylvain , Consiglieri, Gesa , Bouziat, Romain , Urrutia, Alejandra , Graff-Dubois, Stéphanie , Fourati, Slim , Malet, Isabelle , Guergnon, Julien , Guihot, Amélie , Katlama, Christine , Autran, Brigitte , van Endert, Peter , Lemonnier, François A , Appay, Victor , Schwartz, Olivier , Kloetzel, Peter M and Moris, Arnaud
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Cytotoxic CD8+ T cells (CTLs) play a critical role in controlling viral infections. HIV-infected individuals develop CTL responses against epitopes derived from viral proteins, but also against cryptic epitopes encoded by viral alternative reading frames (ARF). We studied here the mechanisms of HIV-1 escape from CTLs targeting one such cryptic epit...
Alternative Titles
Full title
CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope
Authors, Artists and Contributors
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Record Identifier
TN_cdi_plos_journals_1289082112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289082112
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1002049
