Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape
Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape
About this item
Full title
Author / Creator
Bar, Katharine J , Tsao, Chun-yen , Iyer, Shilpa S , Decker, Julie M , Yang, Yongping , Bonsignori, Mattia , Chen, Xi , Hwang, Kwan-Ki , Montefiori, David C , Liao, Hua-Xin , Hraber, Peter , Fischer, William , Li, Hui , Wang, Shuyi , Sterrett, Sarah , Keele, Brandon F , Ganusov, Vitaly V , Perelson, Alan S , Korber, Bette T , Georgiev, Ivelin , McLellan, Jason S , Pavlicek, Jeffrey W , Gao, Feng , Haynes, Barton F , Hahn, Beatrice H , Kwong, Peter D , Shaw, George M and Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Single genome sequencing of early HIV-1 genomes provides a sensitive, dynamic assessment of virus evolution and insight into the earliest anti-viral immune responses in vivo. By using this approach, together with deep sequencing, site-directed mutagenesis, antibody adsorptions and virus-entry assays, we found evidence in three subjects of neutraliz...
Alternative Titles
Full title
Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape
Authors, Artists and Contributors
Author / Creator
Tsao, Chun-yen
Iyer, Shilpa S
Decker, Julie M
Yang, Yongping
Bonsignori, Mattia
Chen, Xi
Hwang, Kwan-Ki
Montefiori, David C
Liao, Hua-Xin
Hraber, Peter
Fischer, William
Li, Hui
Wang, Shuyi
Sterrett, Sarah
Keele, Brandon F
Ganusov, Vitaly V
Perelson, Alan S
Korber, Bette T
Georgiev, Ivelin
McLellan, Jason S
Pavlicek, Jeffrey W
Gao, Feng
Haynes, Barton F
Hahn, Beatrice H
Kwong, Peter D
Shaw, George M
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1289088187
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289088187
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1002721
