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Absence of HIV-1 evolution in the gut-associated lymphoid tissue from patients on combination antivi...

Absence of HIV-1 evolution in the gut-associated lymphoid tissue from patients on combination antivi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289092882

Absence of HIV-1 evolution in the gut-associated lymphoid tissue from patients on combination antiviral therapy initiated during primary infection

About this item

Full title

Absence of HIV-1 evolution in the gut-associated lymphoid tissue from patients on combination antiviral therapy initiated during primary infection

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2012-02, Vol.8 (2), p.e1002506-e1002506

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Mucosal mononuclear (MMC) CCR5+CD4+ T cells of the gastrointestinal (GI) tract are selectively infected and depleted during acute HIV-1 infection. Despite early initiation of combination antiretroviral therapy (cART), gut-associated lymphoid tissue (GALT) CD4+ T cell depletion and activation persist in the majority of HIV-1 positive individuals stu...

Alternative Titles

Full title

Absence of HIV-1 evolution in the gut-associated lymphoid tissue from patients on combination antiviral therapy initiated during primary infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289092882

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289092882

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1002506

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