Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA...
Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Prion diseases typically have long pre-clinical incubation periods during which time the infectious prion particle and infectivity steadily propagate in the brain. Abnormal neuritic sprouting and synaptic deficits are apparent during pre-clinical disease, however, gross neuronal loss is not detected until the onset of the clinical phase. The molecu...
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Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice
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TN_cdi_plos_journals_1289103868
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289103868
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1003002
