REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I
REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I
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United States: Public Library of Science
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English
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United States: Public Library of Science
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RIG-I and MDA5 are cytoplasmic sensors that recognize different species of viral RNAs, leads to activation of the transcription factors IRF3 and NF-kappaB, which collaborate to induce type I interferons. In this study, we identified REUL, a RING-finger protein, as a specific RIG-I-interacting protein. REUL was associated with RIG-I, but not MDA5, t...
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REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I
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TN_cdi_plos_journals_1289156310
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289156310
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0005760