The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development
The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Canonical Wnt signals are transduced through a Frizzled receptor and either the LRP5 or LRP6 co-receptor; such signals play central roles during development and in disease. We have previously shown that Lrp5 is required for ductal stem cell activity and that loss of Lrp5 delays normal mammary development and Wnt1-induced tumorigenesis. Here we show...
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Full title
The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development
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TN_cdi_plos_journals_1289198602
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289198602
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0005813
