Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are ass...
Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration
About this item
Full title
Author / Creator
SanGiovanni, John Paul , Arking, Dan E , Iyengar, Sudha K , Elashoff, Michael , Clemons, Traci E , Reed, George F , Henning, Alice K , Sivakumaran, Theru A , Xu, Xuming , DeWan, Andrew , Agrón, Elvira , Rochtchina, Elena , Sue, Carolyn M , Wang, Jie Jin , Mitchell, Paul , Hoh, Josephine , Francis, Peter J , Klein, Michael L , Chew, Emily Y and Chakravarti, Aravinda
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Age-related macular degeneration (AMD), a chronic neurodegenerative and neovascular retinal disease, is the leading cause of blindness in elderly people of western European origin. While structural and functional alterations in mitochondria (mt) and their metabolites have been implicated in the pathogenesis of chronic neurodegenerative and vascular...
Alternative Titles
Full title
Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration
Authors, Artists and Contributors
Author / Creator
Arking, Dan E
Iyengar, Sudha K
Elashoff, Michael
Clemons, Traci E
Reed, George F
Henning, Alice K
Sivakumaran, Theru A
Xu, Xuming
DeWan, Andrew
Agrón, Elvira
Rochtchina, Elena
Sue, Carolyn M
Wang, Jie Jin
Mitchell, Paul
Hoh, Josephine
Francis, Peter J
Klein, Michael L
Chew, Emily Y
Chakravarti, Aravinda
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1289215573
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289215573
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0005508
