High nucleosome occupancy is encoded at human regulatory sequences
High nucleosome occupancy is encoded at human regulatory sequences
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Active eukaryotic regulatory sites are characterized by open chromatin, and yeast promoters and transcription factor binding sites (TFBSs) typically have low intrinsic nucleosome occupancy. Here, we show that in contrast to yeast, DNA at human promoters, enhancers, and TFBSs generally encodes high intrinsic nucleosome occupancy. In most cases we ex...
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Full title
High nucleosome occupancy is encoded at human regulatory sequences
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TN_cdi_plos_journals_1289259659
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289259659
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0009129
