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High nucleosome occupancy is encoded at human regulatory sequences

High nucleosome occupancy is encoded at human regulatory sequences

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289259659

High nucleosome occupancy is encoded at human regulatory sequences

About this item

Full title

High nucleosome occupancy is encoded at human regulatory sequences

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-02, Vol.5 (2), p.e9129-e9129

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Active eukaryotic regulatory sites are characterized by open chromatin, and yeast promoters and transcription factor binding sites (TFBSs) typically have low intrinsic nucleosome occupancy. Here, we show that in contrast to yeast, DNA at human promoters, enhancers, and TFBSs generally encodes high intrinsic nucleosome occupancy. In most cases we ex...

Alternative Titles

Full title

High nucleosome occupancy is encoded at human regulatory sequences

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289259659

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289259659

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0009129

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