Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool E...
Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN)
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Customized zinc finger nucleases (ZFNs) form the basis of a broadly applicable tool for highly efficient genome modification. ZFNs are artificial restriction endonucleases consisting of a non-specific nuclease domain fused to a zinc finger array which can be engineered to recognize specific DNA sequences of interest. Recent proof-of-principle exper...
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Full title
Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN)
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TN_cdi_plos_journals_1289781445
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289781445
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0004348
