Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase
Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Neutral endopeptidase, also known as neprilysin and abbreviated NEP, is considered to be one of the key enzymes in initial human amyloid-beta (Abeta) degradation. The aim of our study was to explore the impact of NEP deficiency on the initial development of dementia-like symptoms in mice.
We found that while endogenous Abeta concentrations were...
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Full title
Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase
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TN_cdi_plos_journals_1289961839
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289961839
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0004590
