The yeast PNC1 longevity gene is up-regulated by mRNA mistranslation
The yeast PNC1 longevity gene is up-regulated by mRNA mistranslation
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
Translation fidelity is critical for protein synthesis and to ensure correct cell functioning. Mutations in the protein synthesis machinery or environmental factors that increase synthesis of mistranslated proteins result in cell death and degeneration and are associated with neurodegenerative diseases, cancer and with an increasing number of mitoc...
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Full title
The yeast PNC1 longevity gene is up-regulated by mRNA mistranslation
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TN_cdi_plos_journals_1290610300
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1290610300
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0005212