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Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB tra...

Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB tra...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1290610307

Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB transcription factors and non-Hodgkin lymphoma risk

About this item

Full title

Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB transcription factors and non-Hodgkin lymphoma risk

Publisher

United States: Public Library of Science

Journal title

PloS one, 2009-04, Vol.4 (4), p.e5360-e5360

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A promoter polymorphism in the pro-inflammatory cytokine tumor necrosis factor (TNF) (TNF G-308A) is associated with increased non-Hodgkin lymphoma (NHL) risk. The protein product, TNF-alpha, activates the nuclear factor kappa beta (NF-kappaB) transcription factor, and is critical for inflammatory and apoptotic responses in cancer progression. We h...

Alternative Titles

Full title

Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB transcription factors and non-Hodgkin lymphoma risk

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1290610307

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1290610307

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0005360

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