Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cell...
Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The bronchioles of the murine lung are lined by a simple columnar epithelium composed of ciliated, Clara, and goblet cells that together mediate barrier function, mucociliary clearance and innate host defense, vital for pulmonary homeostasis. In the present work, we demonstrate that expression of Sox2 in Clara cells is required for the differentiat...
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Full title
Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells
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TN_cdi_plos_journals_1291896908
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1291896908
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0008248
