Comparative Therapeutic Effects of Velaglucerase Alfa and Imiglucerase in a Gaucher Disease Mouse Mo...
Comparative Therapeutic Effects of Velaglucerase Alfa and Imiglucerase in a Gaucher Disease Mouse Model
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Gaucher disease type 1 is caused by the defective activity of the lysosomal enzyme, acid beta-glucosidase (GCase). Regular infusions of purified recombinant GCase are the standard of care for reversing hematologic, hepatic, splenic, and bony manifestations. Here, similar in vitro enzymatic properties, and in vivo pharmacokinetics and pharmacodynami...
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Full title
Comparative Therapeutic Effects of Velaglucerase Alfa and Imiglucerase in a Gaucher Disease Mouse Model
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TN_cdi_plos_journals_1292137447
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292137447
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0010750
