Evidence that SOX2 overexpression is oncogenic in the lung
Evidence that SOX2 overexpression is oncogenic in the lung
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
SOX2 (Sry-box 2) is required to maintain a variety of stem cells, is overexpressed in some solid tumors, and is expressed in epithelial cells of the lung.
We show that SOX2 is overexpressed in human squamous cell lung tumors and some adenocarcinomas. We have generated mouse models in which Sox2 is upregulated in epithelial cells of the lung duri...
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Full title
Evidence that SOX2 overexpression is oncogenic in the lung
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TN_cdi_plos_journals_1292195317
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292195317
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0011022
