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Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-assoc...

Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-assoc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292197872

Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi

About this item

Full title

Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-10, Vol.5 (10), p.e13519-e13519

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

One virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing. Serum-resistant B. burgdorferi express up to five distinct complement regulator-acquiring surface proteins (CRASP) which interact with complement regulator factor H (CFH) and factor H-like protein 1 (FHL1) or factor H-r...

Alternative Titles

Full title

Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292197872

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292197872

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0013519

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