Active RNA polymerases: mobile or immobile molecular machines?
Active RNA polymerases: mobile or immobile molecular machines?
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United States: Public Library of Science
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English
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United States: Public Library of Science
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It is widely assumed that active RNA polymerases track along their templates to produce a transcript. We test this using chromosome conformation capture and human genes switched on rapidly and synchronously by tumour necrosis factor alpha (TNFalpha); one is 221 kbp SAMD4A, which a polymerase takes more than 1 h to transcribe. Ten minutes after stim...
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Active RNA polymerases: mobile or immobile molecular machines?
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TN_cdi_plos_journals_1292228244
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292228244
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1000419
