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Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed c...

Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292322001

Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells

About this item

Full title

Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-06, Vol.5 (6), p.e11394-e11394

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Lung cancer is the most frequent form of cancer. The survival rate for patients with metastatic lung cancer is approximately 5%, hence alternative therapeutic strategies to treat this disease are critically needed. Recent studies suggest that lipid biosynthetic pathways, particularly fatty acid synthesis and desaturation, are promising molecular ta...

Alternative Titles

Full title

Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292322001

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292322001

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0011394

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