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Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2...

Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292493567

Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoter

About this item

Full title

Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoter

Publisher

United States: Public Library of Science

Journal title

PloS one, 2009-11, Vol.4 (11), p.e7679-e7679

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Channelrhodopsin-2 (ChR2), one of the archea-type rhodopsins from green algae, is a potentially useful optogenetic tool for restoring vision in patients with photoreceptor degeneration, such as retinitis pigmentosa. If the ChR2 gene is transferred to retinal ganglion cells (RGCs), which send visual information to the brain, the RGCs may be repurpos...

Alternative Titles

Full title

Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoter

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292493567

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292493567

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0007679

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