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Common variation in ISL1 confers genetic susceptibility for human congenital heart disease

Common variation in ISL1 confers genetic susceptibility for human congenital heart disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292615297

Common variation in ISL1 confers genetic susceptibility for human congenital heart disease

About this item

Full title

Common variation in ISL1 confers genetic susceptibility for human congenital heart disease

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-05, Vol.5 (5), p.e10855-e10855

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Congenital heart disease (CHD) is the most common birth abnormality and the etiology is unknown in the overwhelming majority of cases. ISLET1 (ISL1) is a transcription factor that marks cardiac progenitor cells and generates diverse multipotent cardiovascular cell lineages. The fundamental role of ISL1 in cardiac morphogenesis makes this an excepti...

Alternative Titles

Full title

Common variation in ISL1 confers genetic susceptibility for human congenital heart disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292615297

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292615297

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0010855

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